John Mccutchan of the Dart team explains that the Dart VM relies on 3 different integer representations — pretty like the Three Musketeer's, there is the small machine integer (smi), the medium (mint) and the big heavy integer (bint). The VM takes care to switch automatically between the three depending on the size of the integer in play.
Within the smi range, which depends on the CPU architecture, integers fit in a register, therefore can be loaded and stored directly in the field instead of being fetched from memory. They also never require memory allocation. Which leads to the performance side of the story: within the smi range, storing an integer in object lists is faster than putting them in a typed list.
Typed lists would have to tag and untags, steps which refer to the VM set of operations to box and unbox smi values without allocation memory or loading the value from a object. The leaner, the better.
On the other hand, typed list have two big capabilities to consider. The garbage collection is very low as typed lists can store never store object references, only numbers. Typed list can also be much more dense therefore an Int8List would require much less memory and make better use of CPU's cache. The smi range principle applies also in typed lists, so playing with numbers within that range provides the best performance.
All in all, what remains of this is that we need to benchmark each approach to find which work the best depending on the situation.