Sprites, as you will know, are used to prevent multiple requests being queued, so with one payload you could get all the sprites for the site.
But with sprites you tend to get lots of additional icons that are used throughout the website that aren't all needed on any single page.
So with http/2 multiplexing, queuing resources is no longer an issue. You get the speed benefit when you only download the files needed for each page.
However you may get better compression by combining some images into a single file, making the overall size of file transfers smaller.
Speed tests run by Benoît Béraud and Alexandre Masselot have given an example of a sprite sheet loading faster than individual sprites. They concluded that sprite sets can still be used to optimise site performance when using http/2 http://blog.octo.com/en/http2-arrives-but-sprite-sets-aint-no-dead/
Extended write up about http/2 by Rachel Andrew can be found here:
https://www.smashingmagazine.com/2016/02/getting-ready-for-http2/