Even if it's possible, in my opinion it has some disadvantages.
In general I like clients to be as simple as possible to avoid maintenance issues. Instead I'd route all client requests through a REST API on my app server. The disadvantages are not related to Kafka, but are common problems of native clients.
Coupling
You're coupling the Android app closely to your messaging infrastructure. If you later decide that a Kafka solution is too much and Plain Old Java would be good enough, you'll first have to update the Android app and wait until enough users do an update.
Network issues + delivery guarantees
Kafka clients also require a direct connection to each of the brokers. Mobile clients can have very inconsistent/spotty network connectivity, making direct client access susceptible to dropped events and overall network connectivity issues.
Authentication
Probably you already have some kind of authentication in your app. You can also create authenticated connections to Kafka. So you'll have two authentication paths, whereas with an app server Kafka only needs to check if the requests are coming from the trusted app server, which means less implementation effort.
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