I may need more information in order to help - are you really saying that you have Datasets with fields labeled F1, F2, F3, ... and that you now need to bind to the actual tables with columns labeled (for example) Id, CustType, IsActive, ... ?
If this is the case then I would suggest using Views that alias each fieldname to be F1, F2,... This may sound like just as much work as your original problem but everything can be automated.
Creating these 100 views can be achieved via a script. This script can be produced by running some smart T-SQL that obtains the schema data stored in SQL Server and outputs the script required.
Have a look at How can I get column names from a table in SQL Server? to get started.
You will probably need to use cursors in your T-SQL to loop through the schema data and output the script to create the views.
Finally, if you need to modify each of your 100 SSRS reports in the same manner then don't forget that each is stored in Report Definition Language (XML) so you may be able to write a small utility that reads each XML file and makes the necessary changes. Don't forget to backup those files first before letting a new utility loose on them.
I hope all this helps and that the answer has not arrived too late.