The only thing I would want is to always set the 'Fit all columns on one page' setting when users open the Print tab in Excel.
And no, they don't want to do it themselves. What a surprise :)
Here is a screenshot of where that is in Excel 2013:
Tried to look for some VBA code like the following but without success.
With Sheets("Print Letter").PageSetup
.FitToPagesWide = 1
.FitToPagesTall = 1
End With