I haven't cleaned up the code yet, but this works for me to set the signature in Outlook 2013. In python (yes I know its ugly and not PEP8).
import _winreg
def set_default():
try:
#this makes it so users can't change it.
outlook_2013_key = _winreg.OpenKey(_winreg.HKEY_CURRENT_USER, r"Software\Microsoft\Office\15.0\Common\MailSettings", 0, _winreg.KEY_ALL_ACCESS)
_winreg.SetValueEx(outlook_2013_key, "NewSignature", 0, _winreg.REG_SZ, "default" )
_winreg.SetValueEx(outlook_2013_key, "ReplySignature", 0, _winreg.REG_SZ, "default" )
# sets the sigs in outlook profile
outlook_2013_base_key = _winreg.OpenKey(_winreg.HKEY_CURRENT_USER, r"Software\Microsoft\Office\15.0\Outlook\Profiles", 0, _winreg.KEY_ALL_ACCESS)
default_profile_2013_tup = _winreg.QueryValueEx(outlook_2013_base_key,'DefaultProfile')
default_profile_2013 = default_profile_2013_tup[0]
print default_profile_2013
outlook_2013_profile_key = _winreg.OpenKey(_winreg.HKEY_CURRENT_USER,
"Software\\Microsoft\\Office\\15.0\\Outlook\\Profiles\\" + default_profile_2013 + "\\9375CFF0413111d3B88A00104B2A6676", 0, _winreg.KEY_ALL_ACCESS)
for i in range(0, 10):
try:
outlook_2013_sub_key_name = _winreg.EnumKey(outlook_2013_profile_key,i)
print outlook_2013_sub_key_name, "sub_key_name"
outlook_2013_sub_key = _winreg.OpenKey(outlook_2013_profile_key, outlook_2013_sub_key_name, 0, _winreg.KEY_ALL_ACCESS)
_winreg.SetValueEx(outlook_2013_sub_key, "New Signature", 0, _winreg.REG_SZ, "default" )
_winreg.SetValueEx(outlook_2013_sub_key, "Reply-Forward Signature", 0, _winreg.REG_SZ, "default" )
except:
pass
except:
print('no 2013 found')