Running under the assumption that the C .h file contains only #defines (and therefore has nothing external to link against), then the following would work with swig 2.0 (http://www.swig.org/) and python 2.7 (tested). Suppose the file containing just defines is named just_defines.h as above:
#define FOO_A 0x3
#define FOO_B 0x5
Then:
swig -python -module just just_defines.h ## generates just_defines.py and just_defines_wrap.c
gcc -c -fpic just_defines_wrap.c -I/usr/include/python2.7 -I. ## creates just_defines_wrap.o
gcc -shared just_defines_wrap.o -o _just.so ## create _just.so, goes with just_defines.py
Usage:
$ python
Python 2.7.3 (default, Aug 1 2012, 05:16:07)
[GCC 4.6.3] on linux2
Type "help", "copyright", "credits" or "license" for more information.
>>> import just
>>> dir(just)
['FOO_A', 'FOO_B', '__builtins__', '__doc__', '__file__', '__name__', '__package__', '_just', '_newclass', '_object', '_swig_getattr', '_swig_property', '_swig_repr', '_swig_setattr', '_swig_setattr_nondynamic']
>>> just.FOO_A
3
>>> just.FOO_B
5
>>>
If the .h file also contains entry points, then you need to link against some library (or more) to resolve those entry points. That makes the solution a little more complicated since you may have to hunt down the correct libs. But for a "just defines case" you don't have to worry about this.