A pros/cons comparison for those modules exists on http://blog.jboss.org/
mod_proxy
* Pros:
o No need for a separate module compilation and maintenance. mod_proxy,
mod_proxy_http, mod_proxy_ajp and mod_proxy_balancer comes as part of
standard Apache 2.2+ distribution
o Ability to use http https or AJP protocols, even within the same
balancer.
* Cons:
o mod_proxy_ajp does not support large 8K+ packet sizes.
o Basic load balancer
o Does not support Domain model clustering
mod_jk
* Pros:
o Advanced load balancer
o Advanced node failure detection
o Support for large AJP packet sizes
* Cons:
o Need to build and maintain a separate module
mod_proxy_*
variants and usemod_jk
in production successfully, for both Tomcat (5.5, 6, 7) and JBoss/WildFly. – Etrem