Image segmentation for screenshots (Region of Interest)

Question

I want to compare Screenshots of different versions (same site) of a web-application. Until now I tried following approaches:

• pixel based comparison
• pixel based fuzzy comparison with Delta E
• segmented based comparison

For the latter I subdivided the screenshot in different parts of the same size and compared them via color histograms.

Now I want to subdivide the image in a more intelligent way. Maybe I could divide it in some regions of interest. Can anyone explain some approaches for that please?

Here is an example for my problem:

Reveille

So, you want to segment only the text parts? – Max

No, I don´t want to segment only the text parts. There should be segmented other elements also. But for first approach the text would be enough. – Reveille

javascript might be an easier option if you are not dealing with screen shots – Effete