var images = document.querySelectorAll('img[usemap]');
images.forEach( function(image) {
var mapid = image.getAttribute('usemap').substr(1);
var imagewidth = image.getAttribute('width');
var imageheight = image.getAttribute('height');
var imagemap = document.querySelector('map[name="'+mapid+'"]');
var areas = imagemap.querySelectorAll('area');
image.removeAttribute('usemap');
imagemap.remove();
// create wrapper container
var wrapper = document.createElement('div');
wrapper.classList.add('imagemap');
image.parentNode.insertBefore(wrapper, image);
wrapper.appendChild(image);
areas.forEach( function(area) {
var coords = area.getAttribute('coords').split(',');
var xcoords = [parseInt(coords[0]),parseInt(coords[2])];
var ycoords = [parseInt(coords[1]),parseInt(coords[3])];
xcoords = xcoords.sort(function(a, b){return a-b});
ycoords = ycoords.sort(function(a, b){return a-b});
wrapper.innerHTML += "<a href='"+area.getAttribute('href')+"' title='"+area.getAttribute('title')+"' class='area' style='left: "+((xcoords[0]/imagewidth)*100).toFixed(2)+"%; top: "+((ycoords[0]/imageheight)*100).toFixed(2)+"%; width: "+(((xcoords[1] - xcoords[0])/imagewidth)*100).toFixed(2)+"%; height: "+(((ycoords[1] - ycoords[0])/imageheight)*100).toFixed(2)+"%;'></a>";
});
});
img {max-width: 100%; height: auto;}
.imagemap {position: relative;}
.imagemap img {display: block;}
.imagemap .area {display: block; position: absolute; transition: box-shadow 0.15s ease-in-out;}
.imagemap .area:hover {box-shadow: 0px 0px 1vw rgba(0,0,0,0.5);}
<!-- Image Map Generated by http://www.image-map.net/ -->
<img src="https://i.imgur.com/TwmCyCX.jpg" width="2000" height="2604" usemap="#image-map">
<map name="image-map">
<area target="" alt="Zirconia Abutment" title="Zirconia Abutment" href="/" coords="3,12,199,371" shape="rect">
<area target="" alt="Gold Abutment" title="Gold Abutment" href="/" coords="245,12,522,371" shape="rect">
<area target="" alt="CCM Abutment" title="CCM Abutment" href="/" coords="564,12,854,369" shape="rect">
<area target="" alt="EZ Post Abutment" title="EZ Post Abutment" href="/" coords="1036,12,1360,369" shape="rect">
<area target="" alt="Milling Abutment" title="Milling Abutment" href="/" coords="1390,12,1688,369" shape="rect">
<area target="" alt="Angled Abutment" title="Angled Abutment" href="/" coords="1690,12,1996,371" shape="rect">
<area target="" alt="Temporary Abutment [Metal]" title="Temporary Abutment [Metal]" href="/" coords="45,461,506,816" shape="rect">
<area target="" alt="Fuse Abutment" title="Fuse Abutment" href="/" coords="1356,461,1821,816" shape="rect">
<area target="" alt="Lab Analog" title="Lab Analog" href="/" coords="718,935,1119,1256" shape="rect">
<area target="" alt="Transfer Impression Coping Driver" title="Transfer Impression Coping Driver" href="/" coords="8,1330,284,1731" shape="rect">
<area target="" alt="Impression Coping [Transfer]" title="Impression Coping [Transfer]" href="/" coords="310,1330,697,1731" shape="rect">
<area target="" alt="Impression Coping [Pick-Up]" title="Impression Coping [Pick-Up]" href="/" coords="1116,1330,1560,1733" shape="rect">
</map>