I've done this for a few years now at large-scale in the retail space. So my belief is that the recommended way to handle multi-tenancy in Cassandra, is not to. No matter how you do it, the tenants will be hit by the "noisy neighbor" problem. Just wait until one tenant runs a BATCH update with 60k writes batched to the same table, and everyone else's performance falls off.
But the bigger problem, is that there's no way you can guarantee that each tenant will even have a similar ratio of reads to writes. In fact they will likely be quite different. That's going to be a problem for options #1 and #2, as disk IOPs will be going to the same directory.
Option #3 is really the only way it realistically works. But again, all it takes is one ill-considered BATCH write to crush everyone. Also, want to upgrade your cluster? Now you have to coordinate it with multiple teams, instead of just one. Using SSL? Make sure multiple teams get the right certificate, instead of just one.
When we have new teams use Cassandra, each team gets their own cluster. That way, they can't hurt anyone else, and we can support them with fewer question marks about who is doing what.