A more future proof and reusable solution would probably be to add a class to either the current element or the span element, depending on your requirements:
document.getElementById("usernameError").className = "color-red";
Or working off Erics solution:
document.getElementById("usernameError").innerHTML = "<span class='color-red'>**Message</span>";
Then in your CSS:
.color-red{
color: #F00;
}
You could obviously also add diff colours and attribute in a much more maintainable way like this.
NOTE: className Returns A String, representing the class, or a space-separated list of classes, of an element.
document.getElementById("usernameError").style.color
function in the next line. – Tocology