I think it's negligible right now.. (one image that's small?)
However, there are some other things to consider:
- Will there be the possiblity of more images in the future?
- Do you gZip your css files?
Reason being..
For every image loaded into css is one less call to the server, which takes time. We all know that from sprites. Even a larger sized sprite, than all the images combined, is preferrable.
That means that every image that's added, is one less potential slowdown, if you use data: URI.
and for the second question.. data: URI is VERY gZip friendly. I mean VERY. We have some legacy css files that are huge. 109 kb huge.. and when we data:URI the image, that inflates into a whopping 246 kb! After gZipping, we are down to 126 kb.
Not to mention.. sprites are not fun to maintain, but there is far less reason to sprite if you are using data: URI.
Hope that helps.
PS. a link regarding data:URI.
http://www.nczonline.net/blog/2010/07/06/data-uris-make-css-sprites-obsolete/#comment-5800
PS PS
check the bottom of that page, to find out more Nicolas has to say about data:URI