The biggest and most obvious distinction is that NiFi is a no-code approach - 99% of NiFi users will never see a line of code. It is a web based GUI with a drag and drop interface to build pipelines.
NiFi can perform ETL, and can be used in batch use cases, but it is geared towards data streams. It is not just about moving data from A to B, it can do complex (and performant) transformations, enrichments and normalisations. It comes out of the box with support for many specific sources and endpoints (e.g. Kafka, Elastic, HDFS, S3, Postgres, Mongo, etc.) as well as generic sources and endpoints (e.g. TCP, HTTP, IMAP, etc.).
NiFi is not just about messages - it can work natively with a wide array of different formats, but can also be used for binary data and large files (e.g. moving multi-GB video files).
NiFi is deployed as a standalone application - it's not a framework or api or library or something that you integrate in to something else. It is a fully self-contained, realised application that is fully featured out of the box with no additional development. Though it can be extended with custom development if required.
NiFi is natively clustered - it expects (but isn't required) to be deployed on multiple hosts that work together as a cluster for performance, availability and redundancy.
So, the two tools are used quite differently - hopefully that helps highlight some of the key differences