Just read your post and I have to say I quite like your approach, it heralds the way many web applications will probably work in the future, with both an element of local storage (for disconnected state) and online storage (the master database - to save all customers records in one place and synch to other client devices).
Here are my answers:
1) Storing JSON on server: I'm not sure I would store the objects as JSON, its possible to do so if your application is quite simple, however this will hamper efforts to use the data (running reports and emailing them on a batch job for example). I would prefer to use JSON for TRANSFERRING the information myself and a SQL database for storing it.
2) NoSQL Approach: I think you've answered your own question there. My preferred approach would be to setup a SQL database now (if the extra resource needed is not a problem), that way you'll save yourself a bit of work setting up the data access layer for NoSQL since you will probably have to remove it in the future. SQLite is a good choice if you dont want a fully-featured RDBMS.
If writing a schema is too much hassle and you still want to save JSON on the server, then you can hash up a JSON object management system with a single table and some parsing on the server side to return relevant records. Doing this will be easier and require less permissioning than saving/deleting files.
3) Security: You mentioned there is no user input at the moment:
"for this use case, the user doesn't
get to enter anything"
However at the begining of the question you also mentioned that the user can
"work on one machine, save, then get
on another machine and load their
stuff"
If this is the case then your application will be storing user data, it doesn't matter that you havent provided a nice GUI for them to do so, you will have to worry about security from more than one standpoint and JSON.parse
or similar tools only solve half the the problem (client-side).
Basically, you will also have to check the contents of your POST request on the server to determine if the data being sent is valid and realistic. The integrity of the JSON object (or any data you are tying to save) will need to be validated on the server (using php or another similar language) BEFORE saving to your data store, this is because someone can easily bypass your javascript-layer "security" and tamper with the POST request even if you didnt intend them to do so and then your application will be sending the evil input out the client anyway.
If you have the server side of things tidied up then JSON.parse
becomes a bit obsolete in terms of preventing JS injection. Still its not bad to have the extra layer, specially if you are relying on remote website APIs to get some of your data.
Hope this is useful to you.