AsyncPro supports only Win32 platform. It cannot be used as-is for Win64 bit.
It contains plenty of 32bit inline ASM code that would have to be replaced either by Pascal code or ported to 64bit ASM code. Besides that part there might be other incompatibilities with Win64 bit platform.
Converting 32-bit Delphi Applications to 64-bit Windows - Inline Assembly Code
If your application contains inline assembly (ASM) code, you need to
examine the ASM code and make the following changes: Mixing of
assembly statements with Pascal code is not supported in 64-bit
applications. Replace assembly statements with either Pascal code or
functions written completely in assembly.
Porting assembly code from IA-32 to Intel 64 cannot be done by simply
copying the code. Consider the architecture specifics, such as the
size of pointers and aligning. You may also want to consult the
processor manual for new instructions. If you want to compile the same
code for different architectures, use conditional defines. See Using
Conditional Defines for Cross-Platform Code in "Using Inline Assembly
Code."
RAD Studio supports Intel x86 through SSE4.2 and AMD 3dNow, and for
x64, Intel/AMD through SSE4.2.
Using Inline Assembly Code
Update:
There is Win64 port of AsyncPro provided by Johan Bontes:
I have a version for Win64 on my Github:
https://github.com/JBontes/AsyncPro
It compiles, but I have not been
able to test it comprehensivly. Feel free to file an issue if you get
stuck anywhere.