1.4.0 introduced "Full Speed Debugging" : In the previous version of HotSpot (prior to 1.4.0), when debugging was enabled, the program executed using only the interpreter. From 1.4.0 , the full performance advantage of HotSpot Technology was available to programs running with debugging enabled. The improved performance allows long running programs to be more easily debugged.
After 1.4.1 there are not performance related enhancement mentioned by oracle in JPDA area. Last one was done in JDK 1.4.0 for Java hotspot client VM and for Java Hotspot Server VM in JDK 1.4.1.
So it is safe to say that no performance improvement could be expected in debugging area from 1.4.1 to the latest version. Otherwise it would have been mentioned by oracle docs.
Sources:
https://docs.oracle.com/javase/8/docs/technotes/guides/jpda/
Please go through the links under the enhancement section of the above link to confirm.