TL;DR: Compile the latest Prism code in anticipation of the new NuGet packages.
First of all a small intro on Prism to get everybody on the same foot. Prism is a MVVM guidance/framework created by Microsoft Patterns & Practices. They released up to version 5 for WPF/Silverlight. Next to that they also released Prism for Windows Runtime for Windows 8 and later updated to Win8.1/WP8.1 RT. These are 2 different codebases with the second one being more lightweight in the aspect of regions etc, but giving very useful support for application lifecycle management. It's a common misconception to think they're the same.
In March, ownership of Prism was transferred to the community as an open source project and is available on GitHub. They decided to move forward, merge the common code in a PCL core assemby and add support for Xamarin Forms.
As of today there is no RTM release of Prism 6 for UWP yet. The codebase is pretty close to be released with only a few minor issues open, but nothing major preventing most users to use the bits already. At this point of time I would tell you to clone the GitHub repository, compile the assemblies and start porting your app. There are a few breaking changes (mainly namespaces), but you should be up and running in no time. Once the RTM packages are available, drop the hard references and use NuGet.
I have already ported one of our smaller apps and I'm planning to port one of the larger LOB ones (over 60 screens) this weekend.
To come back to the discussion which MVVM framework to use. If you have an app of just a few pages, don't bother using a framework and keep your MVVM simple. If you're going for complex LOB apps, these frameworks have their advantages (and of course disadvantages). There are plenty of choices (MVVM Light, Prism, Caliburn Micro, ...) and all of them are good.
The fact that your colleagues choose for Prism might have a reason like Depechie mentioned. In first place I'm thinking about application lifecycle management where Prism has far superior support for.
With a correct use of base classes you should be able to refactor away most of the dependencies from every single ViewModel in case you want to switch to another framework after all.
The major differences (on top of my head) between Prism for Windows Runtime and MVVM Light that you will have to tackle when switching are VisualStateAwarePages, ViewModelLocator (auto vs property for each view), BindableBase for INotifyPropertyChanged and everything about application lifecycle management. Both frameworks are good, but I wouldn't recommend switching a full blown LOB application between them as it's just too much work (introducing possible bugs).