Install pydbg
Source: https://github.com/OpenRCE/pydbg
Unofficial binaries here: http://www.lfd.uci.edu/~gohlke/pythonlibs/#pydbg
from pydbg import *
from pydbg.defines import *
import struct
dbg = pydbg()
path_exe = "C:\\windows\\system32\\calc.exe"
dbg.load(path_exe, "-u amir")
dbg.debug_event_loop()
parameter_addr = dbg.context.Esp #(+ 0x8)
print 'ESP (address) ',parameter_addr
#attach not working under Win7 for me
#pid = raw_input("Enter PID:")
#print 'PID entered %i'%int(pid)
#dbg.attach(int(pid)) #attaching to running process not working
You might want to have a look at PaiMei, although it's not very active right now https://github.com/OpenRCE/paimei
I couldn't get attach() to work and used load instead. Pydbg has loads of functionality, such as read_proccess_memory, write_process_memory etc.
Note that you can't randomly change memory, because an operating system protects memory of other processes from your process (protected mode). Before the x86 processors there were some which allowed all processors to run in real mode, i.e. the full access of memory for every programm. Non-malicious software usually (always?) doesn't read/write other processes' memory.