In python re, you can span from numberic to upper case alpha. So..
import re
test = "01234ABCDEFGHIJKabcdefghijk01234abcdefghijkABCDEFGHIJK"
re.compile(r'[0-f]+').findall(test) # Bad: matches all uppercase alpha chars
## ['01234ABCDEFGHIJKabcdef', '01234abcdef', 'ABCDEFGHIJK']
re.compile(r'[0-F]+').findall(test) # Partial: does not match lowercase hex chars
## ['01234ABCDEF', '01234', 'ABCDEF']
re.compile(r'[0-F]+', re.I).findall(test) # Good
## ['01234ABCDEF', 'abcdef', '01234abcdef', 'ABCDEF']
re.compile(r'[0-f]+', re.I).findall(test) # Good
## ['01234ABCDEF', 'abcdef', '01234abcdef', 'ABCDEF']
re.compile(r'[0-Fa-f]+').findall(test) # Good (with uppercase-only magic)
## ['01234ABCDEF', 'abcdef', '01234abcdef', 'ABCDEF']
re.compile(r'[0-9a-fA-F]+').findall(test) # Good (with no magic)
## ['01234ABCDEF', 'abcdef', '01234abcdef', 'ABCDEF']
That makes the simplest Python UUID regex:
re_uuid = re.compile("[0-F]{8}-([0-F]{4}-){3}[0-F]{12}", re.I)
I'll leave it as an exercise to the reader to use timeit to compare the performance of these.
Enjoy.
Keep it Pythonic™!
NOTE: Those spans will also match :;<=>?@'
so, if you suspect that could give you false positives, don't take the shortcut. (Thank you Oliver Aubert for pointing that out in the comments.)