There actually is a way of generating code pre-build based on the CodeModel provided by Visual Studio Automation: The Project Interface provides a Property "CodeModel" that contains a graph of all model artifacts in that project. You might want to traverse it in order to find classes, interfaces, properties, ... based on which you generate your output code.
dandrejw already mentioned the Tangible T4-Editor. It has got a free template gallery. There is a reusable template "tangible Visual Studio Automation Helper" which should be extremely helpful in your case. Using this template you could solve your issue like this:
This is code within a t4 template detecting all classes that implement INotifyPropertyChanged.
<#
// get a reference to the project of this t4 template
var project = VisualStudioHelper.CurrentProject;
// get all class items from the code model
var allClasses = VisualStudioHelper.GetAllCodeElementsOfType(project.CodeModel.CodeElements, EnvDTE.vsCMElement.vsCMElementClass, false);
// iterate all classes
foreach(EnvDTE.CodeClass codeClass in allClasses)
{
// get all interfaces implemented by this class
var allInterfaces = VisualStudioHelper.GetAllCodeElementsOfType(codeClass.ImplementedInterfaces, EnvDTE.vsCMElement.vsCMElementInterface, true);
if (allInterfaces.OfType<EnvDTE.CodeInterface>()
.Any(i => i.Name == "INotifyPropertyChanged"))
{
#>Render your code here<#
}
}
#>
Put your output code where the code snippet says "Render your code here".