I found this question and some answers very useful, however I did have path problems, so this answer would cover loading library by finding bin directory path.
First solution:
string assemblyName = "library.dll";
string assemblyPath = HttpContext.Current.Server.MapPath("~/bin/" + assemblyName);
Assembly assembly = Assembly.LoadFrom(assemblyPath);
Type T = assembly.GetType("Company.Project.Classname");
Company.Project.Classname instance = (Company.Project.Classname) Activator.CreateInstance(T);
Second solution
string assemblyName = "library.dll";
string assemblyPath = HttpContext.Current.Server.MapPath("~/bin/" + assemblyName);
Assembly assembly = Assembly.LoadFile(assemblyPath);
(Company.Project.Classname) instance = (Company.Project.Classname) assembly.CreateInstance("Company.Project.Classname");
You can use same principle for interfaces (you would be creating a class but casting to interface), such as:
(Company.Project.Interfacename) instance = (Company.Project.Interfacename) assembly.CreateInstance("Company.Project.Classname");
This example is for web application but similar could be used for Desktop application, only path is resolved in different way, for example
Path.GetDirectoryName(Application.ExecutablePath)